Corpo Clínico

Prof. Dr. Rufino Silva


LOCAL DE TRABALHO

Coimbra, Aveiro, Oliveira de Azeméis

 

BREVE CURRICULUM VITAE

Professor Associado de Oftalmologia. Faculdade de Medicina da Universidade de Coimbra.

Chefe da Secção de Retina Médica e Neuroftalmologia do Serviço de Oftalmologia, Centro Hospitalar e Universitário de Coimbra (CHUC).

 

Investigação

Investigador Principal de Projetos de Investigação Nacionais e Internacionais na AIBILI (Associação para a Investigação Biomédica e Inovação em Luz e Imagem) e no iCBR (Instituto de Investigação Clínica e Biomédica de Coimbra: Faculdade de Medicina. Universidade de Coimbra).

Áreas de investigação – Degenerescência macular relacionada com a idade (DMI), Miopia patológica, Oclusões venosas, Retinopatia diabética, Corioretinopatia serosa central.

Orientador de várias Teses de Mestrado e Doutoramento em Oftalmologia.

https://orcid.org/0000-0001-8676-0833 

 

Publicações

Autor de numerosas publicações em revistas científicas nacionais e internacionais.

Revisor e membro do Conselho Editorial de Revistas Científicas Internacionais.

Membro da Sociedade Portuguesa de Oftalmologia, da Academia Americana d Oftalmologia, da Euretina, da Macula Society e do Clube Jules Gonin.

 

Áreas de especialização

Diagnóstico e tratamento das doenças da retina [(tais como a degenerescência macular relacionada com a idade (DMI), a retinopatia diabética, a neovascularização coroideia (associada a doenças como a DMI ou a outra sdoenças como a alta miopia), a coriorretinopatia serosa central ou as oclusões venosas)].

Cirurgia de catarata.

Tratamento com anti-angiogénicos, terapia fotodinâmica e fotocoagulação laser.

 

 

Recent Publications:

Cachulo Mda L, Laíns I, Lobo C, Figueira J, Ribeiro L, Marques JP, Costa J, Vieira A, Rodrigues J, Alves D, Nunes S, Costa M, Rodrigues V, Cunha-Vaz J, Delcourt C, Silva R. Age-related macular degeneration in Portugal: prevalence and risk factors in a coastal and an inland town. The Coimbra Eye Study - Report 2. Acta Ophthalmol. 2016 Sep;94(6):e442-53.

 

Holz FG, Dugel PU, Weissgerber G, Hamilton R, Silva R, Bandello F, Larsen M, Weichselberger A, Wenzel A, Schmidt A, Escher D, Sararols L, Souied E. Single-Chain Antibody Fragment VEGF Inhibitor RTH258 for Neovascular Age-Related Macular Degeneration: A Randomized Controlled Study. Ophthalmology. 2016 May;123(5):1080-9.

 

Campos A, Campos EJ, Martins J, Ambrósio AF, Silva R. Viewing the choroid: where we stand, challenges and contradictions in diabetic retinopathy and diabetic macular oedema. Acta Ophthalmol. 2017 Aug;95(5):446-459.

 

Gil JQ, Marques JP, Hogg R, Rosina C, Cachulo ML, Santos A, Staurenghi G, Chakravarthy U, Silva R. Clinical features and long-term progression of reticular pseudodrusen in age-related macular degeneration: findings from a multicenter cohort. Eye (Lond). 2017 Mar;31(3):364-371.

 

Ferreira JA, Oliveira P, Silva PM, Silva R. Mathematics of aging: Diseases of the posterior segment of the eye. Computers & Mathematics with Applications. 2017;71(1):11-26.

 

Kaszubski PA, Ben Ami T, Saade C, Nabati C, Kumar V, Santos AR, Silva R, Cachulo ML, Cunha-Vaz JG, Smith RT. Changes in reticular pseudodrusen area in eyes that progressed from early to late age-related macular degeneration. Int Ophthalmol. 2017 Mar 7. [Epub ahead of print]

 

Laíns I, Duarte D, Barros AS, Martins AS, Gil J, Miller JB, Marques M, Mesquita T, Kim IK, Cachulo MDL, Vavvas D, Carreira IM, Murta JN, Silva R, Miller JW, Husain D, Gil AM. Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy. PLoS One. 2017 May;12(5):e0177749.

 

Santos AR, Costa MÂ, Schwartz C, Alves D, Figueira J, Silva R, Cunha-Vaz J. Optical Coherence Tomography Baseline Predictors for Initial Best-Corrected Visual Acuity Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment in Eyes with Diabetic Macular Edema: The CHARTRES Study. Retina. 2017 May 2. doi: 10.1097/IAE.0000000000001687. [Epub ahead of print]

 

Laíns I, Miller JB, Park DH, Tsikata E, Davoudi S, Rahmani S, Pierce J, Silva R, Chen TC, Kim IK, Vavvas D, Miller JW, Husain D. Structural Changes Associated with Delayed Dark Adaptation in Age-Related Macular Degeneration.  Ophthalmology. 2017 Sep;124(9):1340-1352.

 

Laíns I, Wang J, Providência J, Mach S, Gil P, Gil J, Marques M, Armstrong G, Garas S, Barreto P, Kim IK, Vavvas D, Miller KW, Husain D, Silva R, Miller JB. Choroidal Changes Associated with Subretinal Drusenoid Deposits in Age-related Macular Degeneration using Swept-source OCT. Am J Ophthalmol. 2017 Aug;180:55-63.

 

Colijn JM, Buitendijk GHS, Prokofyeva E, Alves D, Cachulo ML, Khawaja AP, Cougnard-Gregoire A, Merle BMJ, Korb C, Erke MG, Bron A, Anastasopoulos E, Meester-Smoor MA, Segato T, Piermarocchi S, de Jong PTVM, Vingerling JR; EYE-RISK consortium, Topouzis F, Creuzot-Garcher C, Bertelsen G, Pfeiffer N, Fletcher AE, Foster PJ, Silva R, Korobelnik JF, Delcourt C, Klaver CCW; European Eye Epidemiology (E3) consortium. Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future. Ophthalmology. 2017 Dec;124(12):1753-1763.

 

Laíns I, Kelly RB, Miller JB, Silva R, Vavvas D, Kim IK, Murta JN, Lasky-Su J, Miller JW, Husain D. Human Plasma Metabolomics Study Across all Stages of Age-related Macular Degeneration Identifies Potential Lipid Biomarkers. Ophthalmology. 2017. DOI: http://dx.doi.org/10.1016/j.ophtha.2017.08.008 [Epub ahead of print]

 

Marques JP, Farinha C, Costa MÂ, Ferrão Â, Nunes S, Silva R. Protocol for a randomised, double-masked, sham-controlled phase 4 study on the efficacy, safety and tolerability of intravitreal aflibercept monotherapy compared with aflibercept with adjunctive photodynamic therapy in polypoidal choroidal vasculopathy: the ATLANTIC study. BMJ Open. 2017 Aug;7(8):e015785.

 

Martins A, Farinha C, Raimundo M, Lopes M, Santos AR, Melo P, Marques M, Marques JP, Barreto P, Cachulo ML, Neves C, Cunha-Vaz J, Silva R. Multimodal Evaluation of the Fellow Eye of Patients with Retinal Angiomatous Proliferation. Ophthalmic Res. 2017 Oct 25. doi: 10.1159/000481262. [Epub ahead of print]

 

Layana AG, Minnella AM, Garhöfer G, Aslam T, Holz FG, Leys A, Silva R, Delcourt C, Souied E, Seddon JM. Vitamin D and Age-Related Macular Degeneration. Nutrients. 2017 Oct 13;9(10). pii: E1120.

 

Wang JC, Laíns I, Providência J, Armstrong GW, Santos AR, Gil P, Gil J, Talcott KE, Marques JH, Figueira J, Vavvas DG, Kim IK, Miller JW, Husain D, Silva R, Miller JB. Diabetic Choroidopathy: Choroidal Vascular Density and Volume in Diabetic Retinopathy With Swept-Source Optical Coherence Tomography. Am J Ophthalmol. 2017 Dec;184:75-83.

 

Silva R, Berta A, Larsen M, Macfadden W, Feller C, Monés J; TREND Study Group. Treat-and-Extend versus Monthly Regimen in Neovascular Age-Related Macular Degeneration: Results with Ranibizumab from the TREND Study. Ophthalmology. 2018;125(1):57-65.

© 2018 Rufino Silva - Clínica Oftalmológica
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